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UV Sanitization

The high peak power of pulsed light generated by Xenon's SteriPulse-XL™ systems has been proven to destroy micro organisms of all origins. Pharmaceutical and medical device companies are increasingly turning to pulsed light technology.

Pulsed UV light is particularly useful in applications where continuous mercury UV is unable to meet the requirements for complete DNA destruction, process speed, penetration, low product temperature, personnel safety and process flexibility. Pulsed UV offers faster processing, little or no product temperature buildup, process flexibility, freedom from toxic lamp materials, penetration of plastic packages, and ease of meeting special lamp configuration requirements. The pulsed UV light process is environmentally benign since it does not create or use volatile organic compounds (VOCs) or create suspended airborne particulates.

DNA Damage

The pulsed UV light causes formation of Pyrimidone dimers in DNA, resulting in genetic damage to cells and their ultimate destruction. Types of damage induced by pulsed UV light are: (a) photolysis; (b) loss of colony-forming ability (death); (c) inability to support phage growth (enzyme inactivation) and (d) destruction of nucleic acid.

Food and Drug Administration Approves Pulsed UV Light

Code 21CFR179.41 issued by the Food and Drug Administration (FDA), Department of Health and Human Services, approves the use of Pulsed UV light in the production, processing and handling of food.

Pulsed UV Light Benefits

The most important reasons for considering pulsed UV light systems for sterilization are: